Chromatographic method for estimation of vitamin E from dried blood spot sample

Measurement of Creatinine from Dried Blood spot by Enzymatic Method

Background: DBS on filter paper has been shown as a feasible matrix for collection, transport and analysis of biochemical analytes. Creatinine, is used as a marker of renal function and staging chronic kidney disease (CKD), often requiring repeated testing for drug dosing in patients who undergo dialysis or those who have had arenal transplant. Blood collected and dried on filter paper would be...

Critical sample pretreatment in monitoring dried blood spot citrulline.

BACKGROUND Plasma Citrulline concentration has been correlated to functional enterocyte mass. Dried blood spot (DBS) analysis using LC-MSMS reduces sample amount needed. We optimized DBS elution to increase precision and accuracy of DBS LC-MSMS analysis. METHOD DBS control samples were eluted in varying pH (2.2-7.0) and for varying times (15-75 min) and Cit, Arg and Orn were analyzed using LC...

A digital microfluidic method for dried blood spot analysis.

Blood samples stored as dried blood spots (DBSs) are emerging as a useful sampling and storage vehicle for a wide range of applications. Unfortunately, the surging popularity of DBS samples has not yet been accompanied by an improvement in automated techniques for extraction and analysis. As a first step towards overcoming this challenge, we have developed a prototype microfluidic system for qu...

Validation of the Use of Dried Blood Spot (DBS) Method to Assess Vitamin A Status.

BACKGROUND Vitamin A deficiency is an important dietary deficiency in the world. Thus, the ne¬cessity of screening for deficient populations is obvious. This paper introduces a fast, cheap and relatively reliable method called "dried blood spot" (DBS) method in screening the deficient populations. The validity of this method for retinol measurement was investigated. METHOD The "precision" and...

Estimation of blood phenylalanine from a dried blood spot using the Guthrie test.